Urolithin A, as a secondary metabolite produced by intestinal microbial metabolism of the natural polyphenol compound ellagitannin, has a variety of significant health effects and effects, specifically:
Anti-aging: Urolithin A is known for its powerful antioxidant ability. It can bind to peroxisome proliferator-activated receptor γ (PPARγ), activate the PPARγ signaling pathway, and significantly reduce malondialdehyde in the body. (MDA) and hydrogen peroxide (H2O2) levels, while increasing the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). These enzymes are important antioxidant defenses in the body. System components. Through these mechanisms, urolithin A effectively scavenges free radicals, reduces oxidative damage, protects cells from damage, and thereby delays the cellular aging process. At the same time, it can also promote the function of mitochondria, improve the energy metabolism level of cells, and maintain the vitality and health of cells.
Anti-inflammation: Inflammation is the body’s defense response to injury and infection, but long-term or excessive inflammatory response can accelerate the aging process and lead to a variety of chronic diseases. Urolithin A can inhibit the activity of nuclear factor kappa B (NF-κB) and reduce the production of inflammatory factors, such as C-reactive protein (CRP) and interleukin-6 (IL-6), thereby effectively reducing inflammatory damage. This anti-inflammatory effect is not only beneficial to overall health, but is also particularly important for sensitive skin, because sensitive skin is more susceptible to external stimulation, triggering an inflammatory reaction and accelerating skin aging. Using skin care products containing urolithin A can significantly improve the inflammation of sensitive skin, reduce redness, itching and other symptoms, and keep the skin healthy.
Anti-tumor: Urolithin A also plays an important role in anti-tumor. It can inhibit the growth and spread of tumor cells by inducing apoptosis of tumor cells. Research has found that urolithin A can reduce the proliferation rate and invasiveness of tumor cells. This discovery provides new ideas for cancer treatment, especially for malignant tumors that are difficult to control through traditional treatments. Urolithin A may be able to Become a new auxiliary treatment method.
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