Luteolin, is a naturally occurring compound found in foods including peanut shell, parsley, artichoke leaves, celery, peppers, olive oil, rosemary, lemons, peppermint, sage, thyme, and many others, showed a concentration-dependent inhibitory activity in several models of oxidative stress.
The antioxidant potential of Luteolin, measured in Trolox test, is twice stronger than that of vitamin E. Luteolin is a significantly more potent antioxidant than the synthetic antioxidant butylated hydroxytoluene (BHT), which is generally used in oxygen sensitive processes.
Luteolin has strong scavenging properties for superoxide radicals.
Luteolin is a potent physical quencher of singlet oxygen. Luteolin inhibits single strand break in DNA induced by singlet oxygen in a dose-dependent manner. Chromosomal aberrations are probably one of the causative incidents in the formation of cancer.
Luteolin is more effective than vitamin C and seven other flavonoids in reducing DNA oxidative damage. It also activates the SIRt1 gene.
Luteolin has antioxidant, anti-inflammatory, anti-allergic, and immune-modulating properties to suppress hyperactive immune systems. Luteolin is a potent hypoglycemic agent. Luteolin may help promote healthy blood glucose levels and help in weight management for Syndrome X.
Studies have also shown that luteolin can inhibit uric acid production and promote uric acid excretion. The latter two cytokines play a very important role in the inflammatory mechanism and are sensitive indicators reflecting the degree of inflammation. Luteolin can also increase IFN-γ, reduce specific Ig-E, and reduce the infiltration of eosinophils. In addition, in addition to anti-inflammatory and anti-allergic effects, luteolin also has anti-PDE, anti-SARS, and HIV virus properties. The reason is to inhibit the activity of the pre-S protein of the SARS virus, thereby preventing it from entering the host cell. It is used to treat chronic cough caused by COPD, bronchial asthma, chronic pharyngitis and allergic rhinitis.
The Function of Luteolin
Luteolin is a natural flavonoid that offers several functional properties. Some of its product functionalities for B2B platform product release in English would include:
- Anti-inflammatory: Luteolin possesses anti-inflammatory properties which can be beneficial in skincare products, dietary supplements, and other applications aimed at reducing inflammation.
- Antioxidant: Luteolin acts as an antioxidant, helping to protect against oxidative stress and damage caused by free radicals.
- Anticancer potential: Luteolin has been studied for its potential in cancer prevention and treatment, making it a potential functional ingredient in oncology-related products.
- Neuroprotective effects: Luteolin may offer neuroprotective effects, making it a valuable ingredient in products targeted at cognitive health and neuroprotection.
- Anti-allergic properties: Luteolin has been shown to have anti-allergic properties, making it suitable for use in products aimed at addressing allergic reactions and related symptoms.
- Immune system support: Luteolin may support the immune system, making it a valuable ingredient in products designed to enhance immune function and overall wellness.
- Anti inflammatory demyelinating disease --- luteolin strongly inhibits the phagocytosis of macrophages on myelin sheath in vitro, significantly reducing the production of reactive oxygen species in cells.
- Anti fibrosis --- Luteolin can reduce the degree of liver fibrosis and the expression of hydroxyproline in liver tissue. It can also improve the histopathology changes of pulmonary fibrosis caused by bleomycin and reduce the lung weight index.
- High uric acid resistance --- Luteolin, as a natural flavonoid, has the characteristics of inhibiting the activity of xanthine oxidase, thus inhibiting the formation of uric acid.
- Anti fertility and hormonal effects --- Luteolin has significant dose-dependent anti implantation activity. After oral administration, it can significantly increase the weight, diameter, thickness of the endometrium, and height of its epithelial cells.
- Others --- Luteolin can inhibit a variety of bacteria and viruses, such as Escherichia coli, poliovirus, etc. In addition, luteolin also has immune regulation and blood pressure lowering effects.
Contact Now
