Panax notoginseng extract is the root of Panax notoginseng, a plant of the Araliaceae family. It is mostly cultivated on the slopes at the foot of the mountain or the gentle slopes of the mound at an altitude of 800-1000m, and is mainly produced in Yunnan, Guangxi, Sichuan and other places.
The main components of Panax notoginseng extract: saponins, mainly ginsenosides Rb1, Rg1, Rg2 and a small amount of ginsenosides Ra, Rb2, Rb and Re, and also contain flavonoids, starch, protein, oil, etc. Among them, Panax notoginseng total saponins are its main active ingredients.
Efficacy of Panax notoginseng extract
Bidirectional regulation of hemostasis and blood circulation: Panax notoginseng extract in Panax notoginseng can shrink capillaries and reduce bleeding, and can be used for auxiliary treatment of traumatic bleeding or gastrointestinal bleeding. At the same time, its active ingredients such as saponins have the effect of dilating blood vessels and improving blood circulation, which can promote the dissipation of blood stasis, achieve the effect of blood circulation and blood stasis, and relieve pain and swelling caused by poor blood circulation.
Protection of the cardiovascular system: It can dilate coronary arteries, increase coronary blood flow, and reduce myocardial oxygen consumption; it can reduce arterial pressure and slightly reduce heart rate, and reduce the burden on the heart. It can also reduce platelet aggregation rate and platelet adhesion in vitro, inhibit endothelial cell apoptosis, reduce coronary atherosclerosis, and have a certain preventive and therapeutic effect on cardiovascular diseases such as coronary heart disease, hypertension, and heart failure.
Anti-inflammatory effect: Panax notoginseng total saponins and some of its monomer components such as rg1, re, rd and rb1 have a good down-regulating effect on the anti-inflammatory signaling pathway mapk pathway and nf-κb pathway, can inhibit the production and release of inflammatory factors, reduce tissue edema and pain, and can be used to treat inflammatory diseases such as trauma, muscle soreness, and arthritis.
Improve the body's immunity: Polysaccharides can enhance the phagocytic function of macrophages and the activity of natural killer cells, thereby improving the body's immunity, which is beneficial for people who are susceptible to infection due to low immune function.
Anti-tumor effect: Studies have found that saponins in Panax notoginseng can inhibit the growth and spread of cancer cells, promote apoptosis of tumor cells, and inhibit the invasion and metastasis of cancer cells, and have certain potential in tumor treatment.
Anti-aging effect: Panax notoginseng saponins can scavenge free radicals, inhibit lipid peroxidation, and increase the activity of endogenous antioxidant enzymes in the aging state, delaying aging from multiple aspects, helping to delay skin aging and improve uneven skin color.
Effect on the nervous system: It can affect the central nervous system, improve its function, and promote nerve regeneration and repair. It has a certain improvement effect on nervous system symptoms such as neurasthenia, insomnia, and memory loss.
Application of Panax notoginseng extract
Medical field
Treatment of cardiovascular and cerebrovascular diseases: such as injection powders such as Xuesetong and Xueshuantong, and oral preparations such as Xuesetong tablets and Xuesetong capsules, are widely used in the treatment of coronary heart disease, angina pectoris, myocardial infarction, cerebral infarction, hypertension and other diseases, which can improve the patient's blood circulation, alleviate symptoms, and reduce the risk of recurrence of the disease.
Treatment of trauma and hemorrhagic diseases: It is used to treat various traumatic bleeding, such as knife wounds, abrasions, etc., and can promote wound hemostasis and healing. It can also be used to treat internal bleeding symptoms such as hemoptysis, hematemesis, epistaxis, blood in the stool, and hematuria.
Treatment of other diseases: It also has a certain auxiliary therapeutic effect on diseases such as diabetes complications, hepatitis, and tumors, which can improve the patient's physical condition and improve the quality of life.
Health care products: There are many health care products with Panax notoginseng extract as the main ingredient, which have health care functions such as regulating blood lipids, blood sugar, and blood pressure, enhancing immunity, anti-fatigue, and anti-oxidation. It is suitable for middle-aged and elderly people, people who are under high pressure for a long time, and people with low immunity. It can help maintain physical health and prevent diseases.
Cosmetic field: Due to its anti-inflammatory, skin repair, and anti-aging effects, it is widely used in cosmetics, such as creams, essences, masks, etc., which can promote skin wound healing, improve skin blood circulation, reduce wrinkles, delay skin aging, and make the skin smoother and more delicate.
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