Goji berry extract is an active ingredient extracted from the ripe fruit of Lycium chi-nense Mill or Lycium barbarum L., a plant of the Solanaceae family. It contains Lycium barbarum polysaccharides, carotenoids, fat, protein, free amino acids, taurine, betaine, vitamin B1, vitamin B2, vitamin E, vitamin C, etc.
The Function of Goji Berry Extract
1. Protect visual function
The carotenoids in Lycium barbarum extract, namely zeaxanthin, lutein, β-carotene and various biologically active ingredients such as LBP, TFLB, and betaine, have a synergistic effect in protecting vision. Carotene is converted into vitamin A in the human body, mainly including three molecular forms of retinol, retinal and retinoic acid. Retinal combines with opsin to form rhodopsin. Under the action of weak light, rhodopsin is converted into its isomers to produce dark vision. Carotene can effectively regulate the optic nerve, promote the synthesis or regeneration of rhodopsin in the retina, and maintain the body's normal vision. Lycium barbarum extract has a protective effect on retinal light damage. LBP plays a role in protecting the optic nerve by resisting oxidation, stabilizing the blood-eye barrier, regulating neuroimmunity.
2. Improving reproductive ability
Lycium barbarum extract and its active ingredients can protect the reproductive system by regulating the hypothalamus-pituitary-gonad axis and trace element metabolism. Lycium barbarum juice can increase the serum testosterone concentration of adult males and change the testosterone/cortisol ratio, thereby improving the sexual desire, erectile function and sexual satisfaction of adult males, and enhancing the sexual function and overall satisfaction of adult males. LBP plays a role in repairing male and female gonadal damage by resisting oxidative stress, scavenging free radicals, inhibiting cell apoptosis, enhancing cellular immunity, and regulating hormone balance; LBP can significantly increase the spermatogenic stem cells, epididymal sperm quality and testicular sperm production in the busulfan spermatogenic disorder model mice; LBP can increase the number and activity of sperm, the sex hormone level of kidney yang deficiency rats, and improve the reproductive function of kidney yang deficiency rats; LBP can protect the oxidative stress damage of the corpus cavernosum of DM rats, significantly improve endothelial function, improve erectile ability, and has a therapeutic effect on erectile dysfunction.
3. Prevention and treatment of nervous system diseases
Wolfberry water extract can protect neurons from the neurotoxicity of Aβ amyloid protein, reduce homocysteine-induced neuronal cell death, and play an anti-aging, neuroprotective and anti-Alzheimer's disease role.
4. Anti-depression
Depression is a mental illness characterized by significant and persistent depression, slow thinking and psychomotor inhibition, accompanied by insomnia, anxiety and even suicidal tendencies. Lycium barbarum extract can significantly improve the behavior of depressed rats, regulate the function of the hypothalamus-pituitary-adrenal axis of depressed rats, significantly reduce the cortisol content in the serum of depressed rats, and reduce the expression level of glutamate receptors in the hippocampus of rats, thereby protecting hippocampal neurons.
5. Liver protection
Wolfberry extract increases antioxidant activity by stimulating endogenous factors in the human body, enhances the activity of antioxidant enzymes, reduces the occurrence of lipid peroxidation, protects liver cell membranes, thereby increasing the body's energy reserves, and helps to resist damage to the liver by foreign substances.
6. Bone and joint protection
Lycium barbarum extract can effectively regulate cytokines in osteoporotic rats, alleviate bone decomposition in rats, and achieve the purpose of treating osteoporosis. LBP can inhibit the high expression of anti-human CD151 (monoclonal antibody) and MMP-3 in osteoarthritis, thereby slowing down the occurrence of osteoarthritis.
7. Antioxidation
Proanthocyanidins and TFLB in Lycium barbarum extract have strong antioxidant activity. Lycium barbarum fermentation liquid can remove the content of intracellular reactive oxygen free radicals. LBP can protect aortic endothelial cell damage caused by hydrogen peroxide through antioxidant and anti-apoptosis.
8. Immunity regulation
LBP in the extract can reduce the body's immune response in mice with sciatic nerve injury, thereby promoting the functional recovery of damaged nerves; LBP-X can activate monocytes and enhance the antigen presentation function of monocytes.
9. Delaying aging
Wolfberry extract can significantly increase the levels of SOD, catalase and glutathione peroxidase, increase HYP content, reduce MDA, and play a role in delaying aging by scavenging free radicals.
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