Introduction of Glutathione
Glutathione is a substance that contains γ- Peptide bonds and thiol tripeptides, abbreviated as GSH, are composed of three amino acids: glutamic acid, cysteine, and glycine. They are widely present in animals, plants, and microorganisms and are one of the most important non protein thiol compounds in living organisms. Under physiological conditions, glutathione mainly exists in two forms: reduced glutathione (GSH) and oxidized glutathione (GSSG). More than 95% of natural glutathione in the human body exists in a reduced form. The total content in young adults is about 15 grams, and 1.5-2 grams are synthesized daily, participating in more than 30 major biochemical metabolic functions in the body.
The cells of the human body undergo various physiological reactions every day, and the smooth progress of these reactions cannot be achieved without the assistance or promotion of certain factors. Glutathione is a very important one, which has many active groups and can participate in and affect various reactions. From external manifestations, best glutathione has multiple effects. Through research, it has been found that currently recognized methods include clearing free radicals, antioxidation, liver protection, whitening, freckle removal, delaying skin aging and pigmentation, and promoting the recovery of certain diseases.
The Efficacy of Glutathione
Antioxidant
Natural glutathione is a powerful antioxidant that exists in every cell of the body. It can eliminate excess free radicals such as hydrogen peroxide and peroxide free radicals, protect the thiol groups in proteins from oxidation, repair the damaged thiol groups in proteins, restore the active function of proteins, and make skin cells healthier.
Whitening and lightening spots
The deposition of melanin is an important cause of skin pigmentation. Glutathione whitening can inhibit the production of melanin, decompose existing melanin, prevent the formation of melanin deposition, and thus prevent the formation of pigmentation, gradually removing existing pigmentation.
Enhance skin elasticity
Continuously supplementing with glutathione can provide a favorable growth environment for new muscle cells. Therefore, the proportion of newly formed muscle cells in the epidermal cells of the skin increases, which has a good comprehensive moisturizing effect and makes muscle cells healthier. After drinking enough water, the skin will become smoother, more tender, and more elastic as it removes yellowing.
Anti aging
Glutathione can delay cell aging, accelerate cell regeneration, and thus delay the aging process of the entire human body. Best l glutathione supplement can increase or promote the secretion of (interleukin) human growth hormone, which can regulate and slow down telomere shortening, prolong cell life, and effectively combat aging.
In 2017, scientists conducted a double-blind controlled clinical trial in which the intervention group was divided into a group that supplemented with 250mg of reduced glutathione daily and a group that received the same dose of oxidized glutathione. After 12 weeks of the trial, it was found that both reduced and oxidized glutathione could improve the skin condition of the intervention group. Compared with the control group, all participants had reduced dark spots caused by ultraviolet radiation. Some participants received glutathione supplementation, skin wrinkles decrease and elasticity increases.
Detoxifying
Glutathione tablet has a certain detoxifying effect on carcinogenic substances such as carbon monoxide, CO, heavy metals, organic solvents, and epoxides, and can combine with them to be excreted from the body; Protect against leukopenia caused by radiation, radioactive drugs, or anti-tumor drugs; And it has a detoxifying effect on various carcinogens by assisting liver metabolism, such as aflatoxin.
The Whitening Mechanism of Glutathione
When ultraviolet rays irradiate the skin, a large amount of free radicals are generated, activating the mechanism of melanin production, and glutathione for skin can intervene in the synthesis of melanin.
1. Directly inhibit the activity of tyrosinase
2. Clearing free radicals inhibits the activation of tyrosinase
3. Make the melanin synthesis pathway lean towards melanin (rather than melanin that darkens the skin)
That is to say, glutathione uses for skin can fundamentally inhibit or reduce melanin, prevent melanin deposition, inhibit the generation of spots and freckles, and thus achieve the effect of brightening and lightening the skin.
What Will Happen If There Is A Deficiency in Glutathione?
People are born with natural glutathione in their bodies! A healthy and well nourished person can continuously eliminate toxins from the body. But with factors such as radiation, illness, trauma, medication, stress, pollution, poor diet, and aging, the consumption of glutathione in the human body will become faster and faster. In addition, the body's ability to synthesize glutathione will gradually weaken with age, especially after the age of 25, which will significantly decrease.
The lower the amount of pure glutathione in the body, the more difficult it is to properly handle the threat of environmental harm to health, such as air pollution, electromagnetic radiation, product toxins, junk food, smoking and drinking, high work pressure, and even vigorous exercise, which can lead to excessive consumption of glutathione, loss of cell vitality, aging, tumors, chronic inflammation, neurodegeneration, and chemical poisoning.
The liver is the largest detoxifying organ in the human body, with a high content of glutathione. Glutathione for liver is very important. Best glutathione in liver cells can participate in biological transformation, thereby transforming harmful toxins in the body into harmless substances and excreting them out of the body. Research has shown that a decrease in glutathione levels can cause liver function damage, leading to more and more toxins remaining in the body, thereby causing damage to liver cells and the liver.
How to Supplement Glutathione?
GSH with glutathione is a valuable gene that is innate in the human body for detoxification, antioxidant, and immune enhancement. However, due to the development of modern civilization, pollution, dietary habits, and life pressure, it cannot achieve the desired effect. In order to slow down our own aging rate and skin problems, we can adopt external glutathione supplement to increase the content of our own antioxidant factors. How should we supplement it?
Food Supplementation
In daily life, we can obtain more from food, which comes to our dining table with vegetables, fruits, animal liver, and other foods containing sulfur, such as garlic, onions, cauliflower, water spinach, cabbage, trippuxin, avocado, watermelon, strawberries, turmeric, milk thistle, and biologically active whey protein, all of which can help improve the level of natural glutathione in the body.
Topical skincare products
A study on glutathione whitening cream observed the skin condition of 30 healthy Filipino women for 10 weeks, mainly observing changes in the following parameters: skin elasticity, smoothness, stratum corneum moisture content, and melanin index.
The results showed that the melanin index of the group using glutathione face cream was significantly lower than that of the control group. In the later stage, the skin was smoother and the water content was higher. Therefore, we can use skincare products containing glutathione to reduce the consumption of glutathione in the skin.
