1. Introduction of Vine Tea Extract
Source
Vine tea extract is mainly derived from the stems and leaves of Ampelopsis grossedentata. Ampelopsis grossedentata extract is rich in flavonoids, the most important of which is dihydromyricetin (DMY). The content of dihydromyricetin is relatively high, generally accounting for about 30% - 50% of the dry weight of Ampelopsis grossedentata. In addition, it also contains other flavonoid components such as flavonols and flavonoid glycosides, as well as a small amount of polysaccharides, phenolic acids, amino acids, etc.
2. Efficacy of Vine Tea Extract
Antioxidant effect
The flavonoids in Ampelopsis grossedentata extract have strong antioxidant capacity. They can remove a variety of free radicals in the body, such as superoxide anion radicals (O₂⁻), hydroxyl radicals (・OH) and hydrogen peroxide (H₂O₂).
Taking dihydromyricetin as an example, it can neutralize free radicals by providing hydrogen atoms, thereby preventing the oxidation chain reaction caused by free radicals. This antioxidant effect helps protect cells from oxidative damage, reduces lipid peroxidation, protein oxidation and DNA damage, and is of great significance for delaying aging and preventing chronic diseases (such as cardiovascular disease, cancer, etc.).
For example, in some in vitro cell experiments, after adding rattan tea extract, the survival rate of cells was significantly improved when stimulated by oxidative stress, indicating that rattan tea extract can effectively reduce oxidative damage.
Anti-inflammatory effect
Rencha extract can inhibit the production of signal pathways and inflammatory mediators related to inflammatory response. It can reduce the expression level of inflammatory factors such as interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α).
In animal experiments, for the inflammation model caused by inflammatory inducers, the symptoms of redness, swelling, heat and pain at the inflammatory site were significantly relieved after the administration of rattan tea extract. This is because the flavonoids in rattan tea extract can regulate the activity of inflammatory cells, such as macrophages and neutrophils, inhibiting their release of inflammatory mediators, thereby exerting an anti-inflammatory effect.
Antibacterial effect
Tengcha extract has an inhibitory effect on a variety of bacteria, including common pathogens such as Staphylococcus aureus, Escherichia coli, and Bacillus subtilis.
Its antibacterial mechanism may be related to destroying the cell wall and cell membrane structure of bacteria and affecting the metabolic process of bacteria. For example, dihydromyricetin can insert into the phospholipid bilayer of the bacterial cell membrane, change the permeability of the cell membrane, cause the leakage of substances in the bacteria, and eventually kill the bacteria. This antibacterial property makes tengcha extract have potential application value in food preservation, medicine and health.
Improve cardiovascular health
Tengcha extract helps lower blood lipids. It can inhibit the intestinal absorption of cholesterol and promote the metabolism of cholesterol, thereby reducing the levels of cholesterol and triglycerides in the blood.
At the same time, it also has a certain vasodilatory effect. Flavonoids can regulate the release of nitric oxide (NO) by endothelial cells, which can relax vascular smooth muscle, dilate blood vessels, lower blood pressure, and improve blood circulation. In some animal models of hypertension, the use of rattan tea extract can control blood pressure to a certain extent.
Blood sugar regulation effect
Vine tea extract can regulate blood sugar levels. It can promote insulin secretion and enhance insulin sensitivity, thereby accelerating the cell's uptake and utilization of glucose.
In diabetic mouse model experiments, the use of rattan tea extract can reduce the fasting blood sugar and postprandial blood sugar levels of mice, and also has a certain improvement effect on some complications caused by diabetes, such as kidney damage.
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